Advancements in Graphene-Based Materials for Biosensing Electronics | Semin. DFMT

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Graphene-based sensors have received significant interest due to their unique properties. These properties include high electrical conductivity and high surface area. The 2D structure of graphene allows all carbon atoms to be exposed to the surroundings, making it an ideal platform for adsorbing and detecting molecules, which leads to increased sensitivity. Graphene is also biocompatible, providing a favorable environment for the immobilization of bioreceptors, such as antibodies, enzymes, DNA, and aptamers [1]. Thus, these properties make graphene an appealing transducer material in biosensors. In this presentation, an overview will be provided of the fundamentals and applications of graphene and its derivatives, such as graphene oxide (GO), reduced graphene oxide (rGO), and laser-induced graphene (LIG), in the development of electrochemical sensors and microfibers [2]. The presentation will explore the development of high-sensitivity devices based on graphene field effect transistors (FETs) and low-cost LIG-based electrochemical sensors [3]. Furthermore, a straightforward method based on 3D flow-focusing microfluid devices will be demonstrated to produce GO microfibers, with good control of thickness and length. Additionally, the presentation will explore both thermal and microwave treatments that can obtain rGO microfibers with spectroscopic and electrical properties like CVD graphene. These promising candidates are suitable for the development of flexible FETs and microelectrodes.


Acknowledgments
MackPesquisa, National Council for Scientific and Technological Development (CNPq) (grant No. 408248/2023-8, 313091/2022-6), INCT NanoVida (grant No. 406079/2022-6) and Financiadora de Estudos e Projetos (Finep) (Grant No. 1151/22).
[1] Nguyen, E. P.; Silva, C. C. C. and Merkoçi, A. Nanoscale, 12, 19043, 2020.
[2] Rocha, J. F. et al. Nanoscale, 13, 6752, 2021.
[3] Scroccarello, A. et al. ACS Sens., 9, 598, 2023.